High-potential C112D/M121X (X = M, E, H, L) Pseudomonas aeruginosa azurins.
نویسندگان
چکیده
Site-directed mutagenesis of Pseudomonas aeruginosa azurin C112D at the M121 position has afforded a series of proteins with elevated Cu(II/I) reduction potentials relative to the Cu(II) aquo ion. The high potential and low axial hyperfine splitting (Cu(II) electron paramagnetic resonance A( parallel)) of the C112D/M121L protein are remarkably similar to features normally associated with type 1 copper centers.
منابع مشابه
Outer-sphere effects on reduction potentials of copper sites in proteins: the curious case of high potential type 2 C112D/M121E Pseudomonas aeruginosa azurin.
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ورودعنوان ژورنال:
- Inorganic chemistry
دوره 48 4 شماره
صفحات -
تاریخ انتشار 2009